Searchable abstracts of presentations at key conferences in endocrinology

ea0016p325 | Endocrine tumours | ECE2008

Mutations in the ret proto-oncogene in Romanian patients with multiple endocrine neoplasia type 2

Paun Diana , Duta Carmen , Mohora Maria , Dogaru Cristian , Dumitrache Constantin

Multiple endocrine neoplasia (MEN) is characterized by the occurrence of tumors involving two or more endocrine glands; MEN 2 is defined by medullary thyroid carcinoma in association with phaeochromocytoma and appears in several clinical variants, which may be inherited as autosomal dominant syndromes. Mutational analysis of RET protooncogene has been use in the diagnosis and management of patients and families with MEN 2 variants.Aim: In this study, we ...